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(Posted February 14, 2010) "Gains in life expectancy from lower smoking rates over the next decade will be offset, to some degree, by reductions in life expectancy based on the rise in obesity....even modest weight loss and reductions in smoking at the individual level can have substantial effects on population health."; "Obesity causes more than 100,000 cases of cancer in the United States each year -- and the number will likely rise as Americans get fatter...Having too much body fat causes nearly half the cases of endometrial cancer -- a type of cancer of the uterus -- and a third of esophageal cancer cases."; "Obesity doubles the risk of psoriasis, and almost a third of new cases of psoriasis are attributable to overweight and obesity. Patients with psoriasis have more than a twofold greater risk of myocardial infarction and diabetes than the general population....The common link in the associations is inflammation."; "Compared with women of normal weight at the beginning of pregnancy, overweight mothers had an 18% increased risk of giving birth to a child with certain heart defects..."; "Obesity is linked to a shortened life span because of associated risks for insulin resistance, diabetes, myocardial infarction, stroke, and other morbidities. Even after age 60 years, the incidence of obesity continues to increase with age."; "Obesity alone may be the best predictor of undiagnosed diabetes."; "Obesity raises the risk of stroke regardless of race or sex,...The most obese black women were at 43% higher risk of stroke than the thinnest black women, while the fattest black men had more than three times the stroke risk of their thin counterparts, depending on the measure of obesity used."; "Sad youngsters are more likely to grow up to be fat adults, particularly if the unhappy child is a girl...Measurable emotional problems, including low self-esteem and "an external locus of control" at age 10 were significant predictors of weight gain in adulthood."; "The number of overweight children in the U.S. has tripled in the last 30 years, and more than 17% of children between the ages of 6 and 19 are overweight....Obese children had concentrations of high-sensitivity C-reactive protein, a marker associated with increased risk of developing heart disease, that were ten times higher than those found in lean children. They also had elevated levels of fibrinogen and plasminogen activator inhibitor 1....Obesity in children as young as 7 years old may put them at higher risk of heart disease and stroke later in life, even if they lack other cardiovascular risk factors such as high blood pressure,...reduction (or weight maintenance in many growing children) remains the cornerstone of any intervention in childhood obesity."; "Metabolic obesity was defined by having two or more metabolic risk factors including high triglycerides, low HDL cholesterol, high blood pressure, high fasting plasma glucose, or diabetes....among all overweight patients, both male and female, metabolic health was associated with significantly lower waist circumference."; "The problem with BMI is it doesn't tell you where the fat is,..."Visceral fat is really bad for you."; "Abdominal fat has been associated with heart disease and diabetes, and now to depression... individuals with depression deposit fat around the middle because of the stress hormone cortisol. When experiencing chronic stress or depression, cortisol levels can become permanently elevated. One effect of high cortisol levels is that it directs fat to the visceral regions by activating lipoprotein lipase and inhibiting lipid mobilization...it is more likely that a combination of poor diet and biological factors are working together."; "People who are very overweight often have a lot of fat between their organs internally. In fact, in some instances, the liver can become so packed with fat you can develop a form of hepatitis, and in extreme cases, it can stop functioning altogether,.... The good news: A healthy eating plan can not only help you shed the weight you can see, but also the internal fat layers you don't see."

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